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January, 2016:

E-Cigarette in luggage blamed for smoke, emergency landing

http://www.dailymail.co.uk/wires/ap/article-3402021/E-Cigarette-luggage-blamed-smoke-emergency-landing.html

Hawaiian Airlines says an e-cigarette illegally put in a checked bag may have caused smoke and an emergency landing.

The cargo-smoke indicator in the cockpit lit up during a flight from Honolulu to Maui on Tuesday, an airline spokesman said Friday.

Alex Da Silva said the captain turned on the plane’s fire-suppression system, declared an emergency and landed quickly at the Maui Airport.

After the plane landed, fire crews found two pieces of checked luggage that seemed to have fire damage caused by an e-cigarette in one of the bags, he said.

The Federal Aviation Administration bans electronic cigarettes from checked luggage, although they are allowed in carry-on bags.

Da Silva said that Maui police were investigating. Police did not immediately answer requests for comment.

Can you get drunk from e-cigs? Researchers suggest it’s possible

http://www.wflx.com/story/30964623/can-you-get-drunk-from-e-cigs-researchers-suggest-its-possible

According to a recent Yale University study, people who vape e-cigarettes could inhale enough alcohol to impair motor skills, depending on how much alcohol is contained in the liquid of an e-cig.

The study, performed by Yale’s School of Medicine, had people vape two different types of e-cigs; one that had .4 percent of alcohol and another that had 23.5 percent.

The study showed that some people who vaped e-cigs that contained high levels of alcohol performed poorly in tests on their motor skills, as well as had detectable levels of alcohol in their urine. The study also noted that those studied did not feel impaired after smoking the e-cigarettes.

While the study found that the liquid contained in 75 percent of commercially produced e-cigarettes had less than 1 percent of alcohol, some e-cigs have a much higher proportion of alcohol. Because e-cigarettes are not regulated, it is hard for consumers to know exactly how much alcohol content is in the product.

Another cause for concern, according to the study, is the presence of alcohol reinforcing the addictive properties of both the nicotine and alcohol in the e-cig.

“Given the widespread and unregulated use of e-cigarettes, especially by youth and other vulnerable populations, further studies are needed to evaluate both the acute safety and long-term health risks of using alcohol-containing e-cigarettes,” said Mehmet Sofuoglu, of Yale’s Department of Psychiatry and VA Connecticut Healthcare system, who is senior author of the study.

According to Yale, the study was funded by the New England Mental Illness Research Education Clinical, Centers, the Department of Veterans Affairs, the National Institute for Drug Abuse and FDA Center for Tobacco Products.

The study does not suggest whether e-cigarettes are more or less dangerous than traditional tobacco cigarettes.

Court Overturns Tobacco Company Victory Over FDA on Menthols

http://abcnews.go.com/Health/wireStory/court-overturns-tobacco-company-victory-fda-menthols-36315525

A federal appeals court has ruled that tobacco companies had no basis to challenge a Food and Drug Administration report on menthol cigarettes, which the industry alleged was written by experts with conflicts of interest.

The decision by a three-judge panel overturns a lower court ruling that barred the FDA from using the report and ordered the agency to reform its committee of tobacco advisers.

The 2011 report from the agency’s Tobacco Products Scientific Advisory Committee concluded that menthol flavoring leads to increased smoking rates, particularly among teens, African Americans and those with low incomes. The report said removing the flavoring would make it easier for some smokers to quit.

Cigarette makers Lorillard Inc. and Reynolds American Inc. sued the agency, alleging conflicts of interest by several members who had previously testified against tobacco companies in court.

But Judge Stephen Williams, writing for the court, states that the companies had no legal basis to challenge the makeup of the committee. Williams rejected company arguments that they could be damaged by the apparent conflicts as “too remote and uncertain.” The opinion was issued Friday in the U.S. Court of Appeals for the District of Columbia Circuit.

Despite the victory for the federal government, the ruling may have limited impact on the FDA or its panel. Last year the FDA announced that four members of its tobacco products advisory panel had either resigned or were removed, following the previous court ruling against the agency.

In 2013, the FDA conducted its own review of menthol cigarettes, concluding they pose a greater public health risk than regular cigarettes. But it did not make a recommendation on whether to limit or ban them.

Reynolds American acquired Lorillard last year in a deal worth $25 billion. Reynolds, which is based in Winston-Salem, North Carolina, now sells Lorillard’s top-selling menthol brand, Newport cigarettes.

A spokesman for Reynolds declined to comment, noting “this is pending litigation.”

CTA Letter on submission to the Legco Panel on Health Services

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The case for Ofsmoke: the potential for price cap regulation of tobacco to raise £500 million per year in the UK

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Smoke-free legislation reduces hospital admissions for childhood lower respiratory tract infection

http://tobaccocontrol.bmj.com/content/early/2016/01/14/tobaccocontrol-2015-052541.abstract

Abstract

Background

Previous studies showed reduction of hospital admissions for asthma after implementation of comprehensive smoke-free legislation. We aimed to evaluate the impact of comprehensive smoke-free legislation implemented in Hong Kong in 2007 on hospital admissions for childhood lower respiratory tract infection (LRTI).

Methods

We obtained data on 75 870 hospital admissions for LRTI among children ≤18 years of age between January 2004 and December 2012 from all Hospital Authority hospitals. Using a negative binomial regression model, we assessed the impact of smoke-free legislation on admission counts.

Results

After legislation implementation, there was an immediate effect with a change in the admission count of −33.5% (95% CI −36.4% to −30.5%), and a change in time trend to −13.9% per year (95% CI −16.0% to −11.7%). Overall, the legislation was associated with a net 47.4% reduction in admission counts in the first year. We estimated that the legislation was associated with a reduction of 13 635 admissions in the first 6 years after implementation. The immediate reduction and change in time trend was more apparent among school-age than preschool children.

Conclusions

Implementation of comprehensive smoke-free legislation was associated with a significant reduction in hospital admissions for childhood LRTI.

E-cigarettes WON’T help you quit: Smokers using vapers are ‘28% less likely to ditch traditional cigarettes’

http://www.dailymail.co.uk/health/article-3399947/E-cigarettes-WON-T-help-quit-Smokers-using-vapers-28-likely-ditch-traditional-cigarettes.html

  • E-cigarettes do not help smokers quit their habit, a major study concludes
  • People using ‘vaping’ gadgets are in fact 28% less likely to stop smoking
  • Experts say devices ‘should not be recommended to help smokers quit’
  • Comes two weeks after regulators approved first e-cigarette for medical use, meaning doctors in the UK can prescribe them to patients

E-cigarettes do not help smokers to quit tobacco, a major study has concluded.

Researchers found that people who use ‘vaping’ gadgets are in fact 28 per cent less likely to give up smoking traditional cigarettes.

The findings are a major blow to leading health officials in England, who have repeatedly insisted that e-cigarettes are a key tool to reduce smoking rates.

The study – a systematic review of all available data on the issue – is the largest to assess whether e-cigarettes assist smokers in quitting cigarettes.

Published in the Lancet Respiratory Medicine journal, it concluded that e-cigarettes do not help smokers quit – and should not be recommended for the purpose until there is solid proof that they do.

Public Health England, in a landmark report published last summer, claimed that e-cigarettes are ‘95 per cent’ safe – and called for the devices to be rolled out on the NHS.

That report was widely criticised when it emerged that its headline claim originated in research partly conducted by scientists funded by the e-cigarette industry.

Yet plans to prescribe e-cigarettes as a quit-smoking aid have carried on at full tilt, and two weeks ago the Medicines and Healthcare Products Regulatory Agency approved the first vaping device for medical use.

The e-Voke, an e-cigarette produced by British American Tobacco, is now allowed to be marketed for smoking cessation, which means patients can request the device from their GP.

E-cigarettes contain a liquid form of nicotine that is heated into vapour to be inhaled, avoiding the harm caused by tobacco smoke.

While most experts are agreed that vaping is far safer than smoking tobacco, many are concerned about unresolved safety concerns.

The World Health Organisation has warned that they may be toxic to bystanders, many rail companies have banned people from vaping on trains or in stations, and the Welsh Government is planning to prohibit the practice in restaurants, pubs and offices from 2017.

Europe’s highest legal expert, Dr Juliane Kokott, the advocate general to the European Court of Justice, last month warned that e-cigarettes ‘possibly cause risks to human health’ and that they may even provide a ‘gateway’ for teenagers to go on to smoke tobacco.

She said that regulation is needed, including banning one in four of the strongest devices, and putting health warnings on packaging telling people e-cigarettes contain a ‘highly addictive substance’.

The new study, led by the University of California San Francisco, reviewed 38 studies assessing the link between e-cigarette use and cigarette cessation among adult smokers.

Research author Dr Sara Kalkhoran said: ‘As currently being used, e-cigarettes are associated with significantly less quitting among smokers.

‘E-cigarettes should not be recommended as effective smoking cessation aids until there is evidence that, as promoted and used, they assist smoking cessation.’

Co-author Professor Stanton Glantz added: ‘The irony is that quitting smoking is one of the main reasons both adults and kids use e-cigarettes, but the overall effect is less, not more, quitting.

‘While there is no question that a puff on an e-cigarette is less dangerous than a puff on a conventional cigarette, the most dangerous thing about e-cigarettes is that they keep people smoking conventional cigarettes.

‘The fact that they are freely available consumer products could be important.’

The two main authors of Public Health England’s report last night issued a fierce criticism of the new findings.

Professor Peter Hajek, of Queen Mary University of London, called it ‘grossly misleading’.

The work, he said, looked only at current smokers who had at some point used an e-cigarette – thus excluding any former smokers who may have used exactly such a device to quit.

And Professor Ann McNeill, of King’s College London, said the review was ‘not scientific’.

‘I believe the findings should therefore be dismissed,’ she added.

But Steven Bernstein of Yale School of Medicine, writing in a separate editorial published by The Lancet, said that despite concerns over the data, the study did raise questions about the usefulness of e-cigarettes as quitting aides.

E-cigarettes vapour affects driving

http://www.herald.co.zw/e-cigarettes-vapour-affects-driving/

YALE. — A new Yale University study finds that people who used a commercially available electronic cigarette liquid with a relatively high alcohol level had their motor skills significantly impaired — even though they didn’t feel like they were “buzzed” from the vaporised booze.

E-cigarettes have become increasingly popular in recent years as users seek alternatives to traditional tobacco products, which cause cancer.

The battery-operated e-cigs vaporise a liquid, which contains nicotine and often flavourings.

“They didn’t actually know they were under the influence of alcohol,” said Dr Mehmet Sofuoglu, a professor at the Yale School of Medicine who co-authored the study published in the journal Drug and Alcohol Dependence. “It still influenced their performance.”

“In this study, they had motor impairment, but they didn’t know they were intoxicated.”

Several of the study participants ingested enough alcohol via the e-cigs that metabolised booze was detected in their urine.

Sofuoglu said the findings are “worrisome,” particularly on the heels of new data showing a dramatic upward spike in the number of middle school and high school students using e-cigarettes.

There’s also cause for concern, researchers said, because of the popularity among e-cig users of making their own vaping liquids — which can have higher alcohol levels than commercially sold liquids.

Sofuoglu said the study showed how e-cig users, even if they didn’t end up having enough detectable alcohol in their urine to trigger a DUI charge, could end up being “intoxicated” and too impaired to drive because of how much “more quickly and efficiently” alcohol affected the brain after people inhaled vaporised booze compared to drinking it.

E-cig vapours who use liquids high in alcohol content may be on the track to “a faster level of dependence” on both alcohol and nicotine, Sofuoglu said. — CNBC.

Are e-cigs bad for you? We reveal the facts

http://www.thesun.co.uk/sol/homepage/features/6857765/Are-e-cigs-bad-for-you-We-reveal-the-truth.html

VAPING has become a phenomenon among smokers as the most effective way to quit smoking.

So you might not think they are bad for you so since the government last week gave the green light for e-cigs to be prescribed on the NHS to help people stop smoking.

The Medicines and Healthcare Products Regulatory Agency (MHRA) has awarded a licence to British American Tobacco for its e-Voke device to be prescribed to smokers – which could open the door for other vaping brands to be prescribed by GPs too.

According to NHS regulator, Public Health England e-cigs are “95% less harmful than tobacco”.

But researchers from the University of California published a study which said vaping is no safer than smoking.

They found e-cig vapour damages DNA that could lead to cancer.

There is still little research on e-cigs mainly because they are still so new.

They were only invented in 2003 by a Chinese pharmacist and not much data can be collected over this short period.

Their potential risks or benefits are still not fully understood.

We take a look at how e-cigs may be good or bad for you:

Pros

E-liquid is made up of mainly juices mixed with vegetable glycerine, nicotine and flavouring – all considered harmless.

It doesn’t contain tar – the main reason why smoking is harmful.

It’s the most effective way of quitting smoking. Research shows it is 60 per cent more effective than other methods such as nicotine gum, patches, or going cold turkey.

It’s far less harmful to the people around you than traditional cigarettes.

They do not leave a sticky, unpleasant odour and do not stain teeth or fingernails.

They are a cheaper alternative to smoking.

Cons

Most vapes still contain the addictive drug nicotine – causing cravings.

It contains other ingredients which raises questions about the impact it has on your health.

E-cigs use liquid nicotine – a highly dangerous substance even in small doses. Some testing suggests that some vaporizers release toxic metals during use.

The industry is relatively unregulated.

They have not been studied thoroughly enough to understand potential risks.

There are potentially dangerous advertisements to young people – promoting addictive habits to young people and non-smokers.

The act of vaping is habit-forming.

Verdict:

So, are e-cigs bad for you? The answer still remains a mystery.

The Sun’s GP, Dr Carol Cooper said there is a big question mark around the use of e-cigarettes.

She said: “We don’t know if it’s harmful or not as there is not enough evidence to suggest it’s bad for you.”

She suggests we must use caution around this relatively new product as we don’t know everything about it.

E-cigarettes and smoking cessation in real-world and clinical settings

http://www.thelancet.com/pdfs/journals/lanres/PIIS2213-2600(15)00521-4.pdf

Summary

Background

Smokers increasingly use e-cigarettes for many reasons, including attempts to quit combustible cigarettes and to use nicotine where smoking is prohibited. We aimed to assess the association between e-cigarette use and cigarette smoking cessation among adult cigarette smokers, irrespective of their motivation for using e-cigarettes.

Methods

PubMed and Web of Science were searched between April 27, 2015, and June 17, 2015. Data extracted included study location, design, population, definition and prevalence of e-cigarette use, comparison group (if applicable), cigarette consumption, level of nicotine dependence, other confounders, definition of quitting smoking, and odds of quitting smoking. The primary endpoint was cigarette smoking cessation. Odds of smoking cessation among smokers using e-cigarettes compared with smokers not using e-cigarettes were assessed using a random effects meta-analysis. A modification of the ACROBAT-NRSI tool and the Cochrane Risk of Bias Tool were used to assess bias. This meta-analysis is registered with PROSPERO (number CRD42015020382).

Findings

38 studies (of 577 studies identified) were included in the systematic review; all 20 studies with control groups (15 cohort studies, three cross-sectional studies, and two clinical trials) were included in random effects meta-analysis and sensitivity analyses. Odds of quitting cigarettes were 28% lower in those who used e-cigarettes compared with those who did not use e-cigarettes (odds ratio [OR] 0·72, 95% CI 0·57–0·91). Association of e-cigarette use with quitting did not significantly differ among studies of all smokers using e-cigarettes (irrespective of interest in quitting cigarettes) compared with studies of only smokers interested in cigarette cessation (OR 0·63, 95% CI 0·45–0·86 vs 0·86, 0·60–1·23; p=0·94). Other study characteristics (design, population, comparison group, control variables, time of exposure assessment, biochemical verification of abstinence, and definition of e-cigarette use) were also not associated with the overall effect size (p≥0·77 in all cases).

Interpretation

As currently being used, e-cigarettes are associated with significantly less quitting among smokers.

Funding

National Institutes of Health, National Cancer Institute, FDA Center for Tobacco Products.